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Russell Stitzlein, M.D.Orthopaedic Oncology

Russell Stitzlein, M.D.

Clinical Interests

Dr. Stitzlein is a fellowship-trained orthopaedic oncologist who specializes in the treatment of both adult and pediatric benign and malignant bone & soft tissue tumors, including pelvic and extremity sarcomas and metastatic bone disease. He has specialized training in limb salvage surgery and tumor/endoprosthetic reconstruction. Dr. Stitzlein is the only orthopaedic oncologist in Orange County affiliated with a NCI-Designated Cancer Center. At the Chao Family Comprehensive Cancer Center, Dr. Stitzlein and his colleagues collaborate to provide multidisciplinary treatment of sarcomas and metastatic bone disease. In addition to his oncology practice, Dr. Stitzlein also performs hip and knee replacements.

Research Interests

Dr. Stitzlein has published several research papers and book chapters in his field. His research interests include outcomes following limb salvage surgery in orthopaedic oncology, developing and utilizing custom guides and implants for patients with bone tumors, and he has a keen interest in evaluating and developing methods to improve graduate medical education/residency training.

Conditions Treated

  • Benign Bone Tumors
  • Benign Soft Tissue Tumors
  • Malignant Bone Tumors (eg. Osteosarcoma, Ewing Sarcoma)
  • Malignant Soft Tissue Tumors (eg. Soft Tissue Sarcoma)
  • Metastatic Bone Disease
  • Hip Osteoarthritis
  • Knee Osteoarthritis


Dr. Stitzlein received his medical degree from the Cleveland Clinic Lerner College of Medicine with special qualifications in biomedical research. He completed his orthopaedic surgery residency at the University of Pennsylvania and his fellowship in musculoskeletal oncology at the University of Texas MD Anderson Cancer Center, which is consistently ranked by US News & World Report as the #1 hospital for cancer care. Dr. Stitzlein currently serves as the Chief of Orthopaedic Oncology in the Department of Orthopaedic Surgery at the University of California, Irvine.

Medical Degree

  • Cleveland Clinic Lerner College of Medicine of Case Western Reserve University School of Medicine with Special Qualifications in Biomedical Research, Cleveland, OH


  • Hospital of the University of Pennsylvania, Philadelphia, PA


  • University of Texas MD Anderson Cancer Center, Houston, TX


  • Jacquelin Perry Award for outstanding research concerning the preservation or restoration of musculoskeletal function, Orthopaedic Rehabilitation Association – 2016
  • Best Poster, Orthopaedic Surgery Research Day Symposium, University of Pennsylvania – 2016
  • Academy of Medicine Education Foundation Scholarship,
    Academy of Medicine of Cleveland & Northern Ohio – 2011
  • Physician Investigator Scholarship, Cleveland Clinic Lerner College of Medicine – 2008-2012
  • Franklin County (Ohio) Farm Bureau Scholarship – 2007 & 2008
  • Summa Cum Laude, Miami University – 2007
  • University Honors with Distinction, Miami University – 2007
  • Departmental Honors, Microbiology and Classical Humanities, Miami University – 2007
  • Bishop-Elliott Prize in Classical Humanities, Miami University – 2007
  • Orton K. Stark Microbiology Undergraduate Award, Miami University – 2006
  • Joseph A. Culler Physics Prize for Excellence in Physics, Miami University - 2006
  • Board of Trustees Harrison Scholarship, Miami University – 2003-2007
  • Top Male Scholar-Athlete, Columbus Dispatch, Columbus, Ohio - 2003

Professional Organizations

  • American Academy of Orthopaedic Surgeons
  • Musculoskeletal Tumor Society
  • Western Orthopaedic Association

Board Certifications

  • American Board of Orthopaedic Surgery (Part I) - 2017